Study of the effects of once daily doses of trilostane on cortisol concentrations and responsiveness to adrenocorticotrophic hormone in hyperadrenocorticoid dogs

Bell, R., Neiger, R., McGrotty, Y. and Ramsey, I.K. (2006) Study of the effects of once daily doses of trilostane on cortisol concentrations and responsiveness to adrenocorticotrophic hormone in hyperadrenocorticoid dogs. Veterinary Record, 159(9), pp. 277-281. (doi:10.1136/vr.159.9.277) (PMID:16946310)

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Abstract

The effects of trilostane, a 3β-hydroxysteroid dehydrogenase inhibitor on basal cortisol concentrations and the results of ACTH stimulation tests in dogs with pituitary-dependent hyperadrenocorticism were investigated. In eight of nine dogs trilostane suppressed the concentration of cortisol below the lower limit of the reference range (<50 nmol/l) for a mean (sd) of 3

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Bell, Mr Rory and Ramsey, Professor Ian
Authors: Bell, R., Neiger, R., McGrotty, Y., and Ramsey, I.K.
College/School:College of Medical Veterinary and Life Sciences > School of Veterinary Medicine
Journal Name:Veterinary Record
Publisher:BMJ Publishing Group
ISSN:0042-4900
ISSN (Online):2042-7670

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