Spinal epidermoid cyst in a SJL mouse: case report and literature review

Hansmann, F., Herder, V. , Ernst, H. and Baumgärtner, W. (2011) Spinal epidermoid cyst in a SJL mouse: case report and literature review. Journal of Comparative Pathology, 145(4), pp. 373-377. (doi: 10.1016/j.jcpa.2011.03.002) (PMID:21511270)

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This report is the first description of a spinal epidermoid cyst (EC) in a SJL mouse and gives an overview on the occurrence of ECs in animals including dogs, horses, mice and rats. The EC was not detected grossly and the mouse did not display clinical signs or an altered rotarod performance. Microscopically, there was an oval cyst lined by stratified squamous epithelium that was attached to the dorsolateral meninges and caused moderate compression of the adjacent lumbar spinal cord. ECs in mice and rats are mainly located in the caudal part of the spinal cord with a variable, strain-dependent occurrence. ECs in mice and rats are not associated with clinical signs and can be interpreted as incidental findings.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Herder, Dr Vanessa
Authors: Hansmann, F., Herder, V., Ernst, H., and Baumgärtner, W.
College/School:College of Medical Veterinary and Life Sciences > School of Infection & Immunity > Centre for Virus Research
Journal Name:Journal of Comparative Pathology
ISSN (Online):1532-3129
Published Online:20 April 2011

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