Impulsivity, aggression, and suicide: a systematic review and meta-analysis

Moore, F. R., Doughty, H., Neumann, T., McClelland, H., Allott, C. and O'Connor, R. C. (2022) Impulsivity, aggression, and suicide: a systematic review and meta-analysis. EClinicalMedicine, 45, 101307. (doi: 10.1016/j.eclinm.2022.101307) (PMID:35243273) (PMCID:PMC8860929)

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Background The aim of the study was to crystallize the nature of relationships between impulsivity, aggression, and suicidality. We reviewed studies of adults with published, psychometric measures of impulsivity and aggression, and measures of suicidality. Methods Our primary data source was Web of Science (from inception to 31st December 2021). Quality of articles was assessed using a Joanna Briggs Appraisal Tool and publication bias using Trim and Fill. We synthesised results using random effects meta-analyses and explored moderation by measure of impulsivity, aggression, and suicidality, and population. Findings 77 studies were included in our analysis. We found weak positive relationships between impulsivity (r = 0·19 [95% CI: 0·15–0·22]), aggression (0·23 ([0·17, 0·29]), and impulsive aggression (0·16 [0·1, 0·22]) with suicidality. Heterogeneity was significant and only partially explained by moderators. Limitations included the lack of studies which assess impulsivity or aggression proximal to suicidality. Interpretation Given small effect sizes and significant heterogeneity, the study suggests that additional studies are needed in the field to analyze the relation between impulsivity and aggression with suicidality.

Item Type:Articles
Glasgow Author(s) Enlighten ID:O'Connor, Professor Rory and Moore, Fhionna and Allott, Claire and Mcclelland, Miss Heather
Authors: Moore, F. R., Doughty, H., Neumann, T., McClelland, H., Allott, C., and O'Connor, R. C.
College/School:College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > Mental Health and Wellbeing
Journal Name:EClinicalMedicine
Publisher:Lancet Publishing Group
ISSN (Online):2589-5370
Published Online:18 February 2022
Copyright Holders:Copyright © 2022 The Authors
First Published:First published in EClinicalMedicine 45:101307
Publisher Policy:Reproduced under a Creative Commons licence

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