Dosimetric gelator probes and their application as sensors

Panja, S. (2022) Dosimetric gelator probes and their application as sensors. Journal of the Indian Chemical Society, 99(3), 100359. (doi: 10.1016/j.jics.2022.100359)

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Supramolecular gels formed by the self-assembly of organic molecules are useful in many areas from materials to medicine. Of the different applications, exploitation of gels for the visual detection of analytes is a fairly recent trend in gel chemistry. Most of the gel-based sensors rely on non-covalent interactions between the gelator molecules and the added chemical analytes and therefore, often suffer from less selectivity and long response time. In this context, dosimetric gelator probes are superior to other gel-based sensors with high selectivity and fast response time. Unlike non-covalent binding sites, dosimetric gelators typically contain a reaction centre and undergo a specific chemical reaction selective to an analyte resulting in either formation or rupturing of covalent bonds. In this review, we provide an up-to-date report of various reaction-based gel systems applied for the sensing of analytes. We elaborately discuss the concept, design principles, self-assembly properties, and reaction mechanisms of such gelators. We also highlight the limitations, challenges, and the necessity of further exploration of dosimetric gels in this domain.

Item Type:Articles
Additional Information:SP thanks the University of Glasgow for funding.
Glasgow Author(s) Enlighten ID:Panja, Dr Santanu
Authors: Panja, S.
College/School:College of Science and Engineering > School of Chemistry
Journal Name:Journal of the Indian Chemical Society
Published Online:19 January 2022
Copyright Holders:Copyright © 2022 Indian Chemical Society
First Published:First published in Journal of the Indian Chemical Society 99(3): 100359
Publisher Policy:Reproduced in accordance with the publisher copyright policy

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