Gastric cancer in Iran: epidemiology and risk factors

Malekzadeh, R., Derakhshan, M.H. and Malekzadeh, Z. (2009) Gastric cancer in Iran: epidemiology and risk factors. Archives of Iranian Medicine, 12(6), pp. 576-583.

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Abstract

Although the global incidence of gastric cancer has been decreased dramatically in recent decades, it is the most common cancer in north and northwest Iran. The wide variation in incidence across different geographical areas and higher proportion of cardia cancer are two main characteristics of gastric cancer in Iran. Current investigations indicate that a high prevalence of H.pylori infection, high dietary intake of salt and smoking are the main environmental factors of gastric cancer in Iran. Gastroesophageal reflux disease is another contributing factor in populations with a higher incidence of gastric cardia cancer. While interventions on modifiable environmental risk factors should be considered as the main modality to reduce gastric cancer development, surveillance programmes for early detection of cancer in highly selected groups may increase overall survival rates in potential patients in this country.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Derakhshan, Dr Mohammad
Authors: Malekzadeh, R., Derakhshan, M.H., and Malekzadeh, Z.
Subjects:R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer)
College/School:College of Medical Veterinary and Life Sciences
Journal Name:Archives of Iranian Medicine
ISSN:1029-2977

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