Natural human infections with Plasmodium cynomolgi and other malaria species in an elimination setting in Sabah, Malaysia

Grignard, L., Shah, S., Chua, T. H., William, T., Drakeley, C. J. and Fornace, K. M. (2019) Natural human infections with Plasmodium cynomolgi and other malaria species in an elimination setting in Sabah, Malaysia. Journal of Infectious Diseases, 220(12), pp. 1946-1949. (doi: 10.1093/infdis/jiz397) (PMID:31418017) (PMCID:PMC6834065)

Abstract

To determine the presence and species composition of malaria infections, we screened a subset of samples collected during a cross-sectional survey in Northern Sabah, Malaysia using highly sensitive molecular techniques. Results identified 54 asymptomatic submicroscopic malaria infections, including a large cluster of Plasmodium falciparum and 3 P. knowlesi infections. We additionally identified 2 monoinfections with the zoonotic malaria Plasmodium cynomolgi, both in individuals reporting no history of forest activities or contact with macaques. Results highlight the need for improved surveillance strategies to detect these infections and determine public health impacts.

• Item Type: Articles
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Fornace, Dr Kimberly
• Authors: Grignard, L., Shah, S., Chua, T. H., William, T., Drakeley, C. J., and Fornace, K. M.
• College/School: College of Medical Veterinary and Life Sciences > School of Biodiversity, One Health & Veterinary Medicine
• Journal Name: Journal of Infectious Diseases
• Publisher: Oxford University Press
• ISSN: 0022-1899
• ISSN (Online): 1537-6613
• Published Online: 16 August 2019
• Copyright Holders: Copyright © 2019 The Authors
• First Published: First published in Journal of Infectious Diseases 220(12): 1946-1949
• Publisher Policy: Reproduced under a Creative Commons License