Natural human infections with Plasmodium cynomolgi and other malaria species in an elimination setting in Sabah, Malaysia

Grignard, L., Shah, S., Chua, T. H., William, T., Drakeley, C. J. and Fornace, K. M. (2019) Natural human infections with Plasmodium cynomolgi and other malaria species in an elimination setting in Sabah, Malaysia. Journal of Infectious Diseases, 220(12), pp. 1946-1949. (doi: 10.1093/infdis/jiz397) (PMID:31418017) (PMCID:PMC6834065)

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Abstract

To determine the presence and species composition of malaria infections, we screened a subset of samples collected during a cross-sectional survey in Northern Sabah, Malaysia using highly sensitive molecular techniques. Results identified 54 asymptomatic submicroscopic malaria infections, including a large cluster of Plasmodium falciparum and 3 P. knowlesi infections. We additionally identified 2 monoinfections with the zoonotic malaria Plasmodium cynomolgi, both in individuals reporting no history of forest activities or contact with macaques. Results highlight the need for improved surveillance strategies to detect these infections and determine public health impacts.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Fornace, Dr Kimberly
Authors: Grignard, L., Shah, S., Chua, T. H., William, T., Drakeley, C. J., and Fornace, K. M.
College/School:College of Medical Veterinary and Life Sciences > Institute of Biodiversity Animal Health and Comparative Medicine
College of Medical Veterinary and Life Sciences > School of Biodiversity, One Health & Veterinary Medicine
Journal Name:Journal of Infectious Diseases
Publisher:Oxford University Press
ISSN:0022-1899
ISSN (Online):1537-6613
Published Online:16 August 2019
Copyright Holders:Copyright © 2019 The Authors
First Published:First published in Journal of Infectious Diseases 220(12): 1946-1949
Publisher Policy:Reproduced under a Creative Commons License

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