Thornhill, J.A., McVeigh, P., Jurberg, A.D. and Kusel, J.R. (2010) Pathways for the influx of molecules into cercariae of Schistosoma mansoni during skin penetration. Parasitology, pp. 1-10. (doi: 10.1017/S0031182009991983)
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Publisher's URL: http://dx.doi.org/10.1017/S0031182009991983
Abstract
It has been observed that fluorescent membrane-impermeant molecules can enter the cercariae as they penetrate mouse skin. The hypothesis to be tested was that such molecules, which included Lucifer Yellow and a variety of fluorescent dextrans, entered the parasite through the nephridiopore and excretory tubules as well as through the surface membrane. FITC-labelled poly-L-lysine (molecular weight 10 kDa), added at 4C. Since increased uptake of propidium iodide occurs when membranes become permeable, the surface membrane could also be a pathway of transport of the membrane-impermeant molecules into the schistosomulum
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Kusel, Professor John |
Authors: | Thornhill, J.A., McVeigh, P., Jurberg, A.D., and Kusel, J.R. |
Subjects: | Q Science > QR Microbiology |
College/School: | College of Medical Veterinary and Life Sciences |
Journal Name: | Parasitology |
ISSN: | 0031-1820 |
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