Barrett, M.P., Bakker, B.M. and Breitling, R. (2010) Metabolomic systems biology of trypanosomes. Parasitology, 137(9), pp. 1285-1290. (doi: 10.1017/S003118201000017X) (PMID:20158937)
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Abstract
Metabolomics analysis, which aims at the systematic identification and quantification of all metabolites in biological systems, is emerging as a powerful new tool to identify biomarkers of disease, report on cellular responses to environmental perturbation, and to identify the targets of drugs. Here we discuss recent developments in metabolomic analysis, from the perspective of trypanosome research, highlighting remaining challenges and the most promising areas for future research.
Item Type: | Articles |
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Keywords: | Metabolomics, mass spectrometry, Orbitrap; ab initio networks, Trypanosoma brucei |
Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Breitling, Professor Rainer and Barrett, Professor Michael |
Authors: | Barrett, M.P., Bakker, B.M., and Breitling, R. |
Subjects: | Q Science > QR Microbiology |
College/School: | College of Medical Veterinary and Life Sciences > School of Infection & Immunity College of Medical Veterinary and Life Sciences > School of Molecular Biosciences |
Journal Name: | Parasitology |
Publisher: | Cambridge University Press |
ISSN: | 0031-1820 |
ISSN (Online): | 1469-8161 |
Published Online: | 17 February 2010 |
Copyright Holders: | Copyright © 2010 Cambridge University Press |
First Published: | First published in Parasitology 137(9):1285-1290 |
Publisher Policy: | Reproduced in accordance with the copyright policy of the publisher |
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