FlyAtlas 2 in 2022: enhancements to the Drosophila melanogaster expression atlas

Krause, S. A. , Overend, G. , Dow, J. A.T. and Leader, D. P. (2022) FlyAtlas 2 in 2022: enhancements to the Drosophila melanogaster expression atlas. Nucleic Acids Research, 50(D1), D1010-D1015. (doi: 10.1093/nar/gkab971) (PMID:34718735) (PMCID:PMC8728208)

[img] Text
253937.pdf - Published Version
Available under License Creative Commons Attribution.



FlyAtlas 2 ( is a database and web application for studying the expression of the genes of Drosophila melanogaster in different tissues of adults and larvae. It is based on RNA-Seq data, and incorporates both genes encoding proteins and microRNAs. We have now completed the population of the database with 13 tissues from both male and female adults, five sex-specific tissues, and eight larval tissues. Larval garland cell nephrocytes have also been included. Major enhancements have been made to the application. First, a facility has been added for a ‘Profile’ search for genes with a similar pattern of tissue expression as a query gene. This may help establish the function of genes for which this is currently unknown. Second, a facility has been added dedicated to the larval midgut, where the difference in gene expression in the five regions of different pH can be explored. A variety of further improvements to the interface are described.

Item Type:Articles
Additional Information:Biotechnology and Biological Sciences Research Council [BB/K019953/1]. Funding for open access charge: Read and Publish agreement between OUP and the University of Glasgow.
Glasgow Author(s) Enlighten ID:Leader, Dr David and Overend, Dr Gayle and Krause, Dr Sue and Dow, Professor Julian
Authors: Krause, S. A., Overend, G., Dow, J. A.T., and Leader, D. P.
College/School:College of Medical Veterinary and Life Sciences
College of Medical Veterinary and Life Sciences > School of Molecular Biosciences
Journal Name:Nucleic Acids Research
Publisher:Oxford University Press
ISSN (Online):1362-4962
Published Online:29 October 2021
Copyright Holders:Copyright © 2021 The Authors
First Published:First published in Nucleic Acids Research 50(D1):D1010–D1015
Publisher Policy:Reproduced under a Creative Commons License

University Staff: Request a correction | Enlighten Editors: Update this record

Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
168236FlyAtlas2: a definitive, expanded NGS expression resource for the Drosophila community and beyond.Julian DowBiotechnology and Biological Sciences Research Council (BBSRC)BB/K019953/1MCSB - Integrative & Systems Biology