Krause, S. A. , Overend, G. , Dow, J. A.T. and Leader, D. P. (2022) FlyAtlas 2 in 2022: enhancements to the Drosophila melanogaster expression atlas. Nucleic Acids Research, 50(D1), D1010-D1015. (doi: 10.1093/nar/gkab971) (PMID:34718735) (PMCID:PMC8728208)
![[img]](https://eprints.gla.ac.uk/style/images/fileicons/text.png) |
Text
253937.pdf - Published Version Available under License Creative Commons Attribution. 2MB |
Abstract
FlyAtlas 2 (flyatlas2.org) is a database and web application for studying the expression of the genes of Drosophila melanogaster in different tissues of adults and larvae. It is based on RNA-Seq data, and incorporates both genes encoding proteins and microRNAs. We have now completed the population of the database with 13 tissues from both male and female adults, five sex-specific tissues, and eight larval tissues. Larval garland cell nephrocytes have also been included. Major enhancements have been made to the application. First, a facility has been added for a ‘Profile’ search for genes with a similar pattern of tissue expression as a query gene. This may help establish the function of genes for which this is currently unknown. Second, a facility has been added dedicated to the larval midgut, where the difference in gene expression in the five regions of different pH can be explored. A variety of further improvements to the interface are described.
| Item Type: | Articles |
|---|---|
| Additional Information: | Biotechnology and Biological Sciences Research Council [BB/K019953/1]. Funding for open access charge: Read and Publish agreement between OUP and the University of Glasgow. |
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Leader, Dr David and Overend, Dr Gayle and Krause, Dr Sue and Dow, Professor Julian |
| Authors: | Krause, S. A., Overend, G., Dow, J. A.T., and Leader, D. P. |
| College/School: | College of Medical Veterinary and Life Sciences College of Medical Veterinary and Life Sciences > School of Molecular Biosciences |
| Journal Name: | Nucleic Acids Research |
| Publisher: | Oxford University Press |
| ISSN: | 0305-1048 |
| ISSN (Online): | 1362-4962 |
| Published Online: | 29 October 2021 |
| Copyright Holders: | Copyright © 2021 The Authors |
| First Published: | First published in Nucleic Acids Research 50(D1):D1010–D1015 |
| Publisher Policy: | Reproduced under a Creative Commons License |
University Staff: Request a correction | Enlighten Editors: Update this record
Altmetric
Altmetric