Multi-aperture Fourier ptychographic microscopy, theory and validation

Konda, P. C. , Taylor, J. M. and Harvey, A. R. (2021) Multi-aperture Fourier ptychographic microscopy, theory and validation. Optics and Lasers in Engineering, 138, 106410. (doi: 10.1016/j.optlaseng.2020.106410)

Abstract

We present a novel microscopy concept, termed Multi-Aperture Fourier ptychographic microscopy (MA-FPM), to enable implementation of parallel detectors in microscopy to increase the space-bandwidth-time product. MA-FPM is a synthetic aperture technique: an array of objectives together with tilt-shift illumination are used to synthesize high-resolution, wide field-of-view images. Here, the phase is recovered using Fourier ptychography (FP) algorithms unlike conventional optical synthetic aperture techniques where holographic measurements are used. In this article we report a proof-of-concept experiment by translating a lens and a detector to positions according to the proposed design and demonstrate high-quality imaging performance despite using nine-fold fewer illumination angles compared to an equivalent FP setup. Calibration procedures and a reconstruction algorithm were developed to address the challenges of multiple imaging systems.

• Item Type: Articles
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Taylor, Dr Jonathan and Konda, Mr Pavan and Harvey, Professor Andy

Creator Roles

Konda, P. C.: Conceptualization, Methodology, Software, Validation, Formal analysis, Investigation, Data curation, Writing – original draft, Writing – review and editing, Visualization
Taylor, J. M.: Conceptualization, Methodology, Writing – original draft, Writing – review and editing, Supervision
Harvey, A. R.: Conceptualization, Methodology, Writing – original draft, Writing – review and editing, Visualization, Resources, Supervision, Project administration, Funding acquisition

• Authors: Konda, P. C., Taylor, J. M., and Harvey, A. R.
• College/School: College of Science and Engineering > School of Physics and Astronomy
• Journal Name: Optics and Lasers in Engineering
• Publisher: Elsevier
• ISSN: 0143-8166
• ISSN (Online): 1873-0302
• Published Online: 12 October 2020