Enhancement of the mechanical properties of lysine-containing peptide-based supramolecular hydrogels by chemical cross-linking

Marshall, L. J., Matsarskaia, O., Schweins, R. and Adams, D. (2021) Enhancement of the mechanical properties of lysine-containing peptide-based supramolecular hydrogels by chemical cross-linking. Soft Matter, 17(37), pp. 8459-8464. (doi: 10.1039/D1SM01136G) (PMID:34494056)

Abstract

Exposure of lysine-containing peptide-based gelators to the cross-linking agent glutaraldehyde allows tuning of gel mechanical properties. The effect of cross-linking depends on the position of the lysine residue in the peptide chain, the concentration of gelator and the conditions under which cross-linking takes place. Through control of these factors, cross-linking leads to increased gel strength.

• Item Type: Articles
• Additional Information: L. J. M. thanks the Leverhulme Trust for funding (RPG-2019-165). The experiment at the Institut Laue-Langevin was allocated beam time under experiment number 9-11-1970 (DOI: 10.5291/ILL-DATA.9-10-1670). This work benefited from the use of the SasView application, originally developed under NSF award DMR-0520547. SasView contains code developed with funding from the European Union’s Horizon 2020 research and innovation programme under the SINE2020 project, grant agreement No 654000.
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Adams, Dave and Marshall, Miss Libby
• Authors: Marshall, L. J., Matsarskaia, O., Schweins, R., and Adams, D.
• College/School: College of Science and Engineering > School of Chemistry
• Journal Name: Soft Matter
• Publisher: Royal Society of Chemistry
• ISSN: 1744-683X
• ISSN (Online): 1744-6848
• Published Online: 30 August 2021
• Copyright Holders: Copyright © 2021 The Royal Society of Chemistry
• First Published: First published in Soft Matter 17(27): 8459-8464
• Publisher Policy: Reproduced under a Creative Commons License

Project Code	Award No	Project Name	Principal Investigator	Funder's Name	Funder Ref	Lead Dept
305912		Spatially- and temporally-controlled photothermal Gels	Dave Adams	Leverhulme Trust (LEVERHUL)	RPG-2019-165	Chemistry