Addressing the post-acute sequelae of SARS-CoV-2 infection: a multidisciplinary model of care

Parker, A. M. et al. (2021) Addressing the post-acute sequelae of SARS-CoV-2 infection: a multidisciplinary model of care. Lancet Respiratory Medicine, 9(11), pp. 1328-1341. (doi: 10.1016/S2213-2600(21)00385-4) (PMID:34678213) (PMCID:PMC8525917)

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Abstract

As of July 31, 2021, SARS-CoV-2 had infected almost 200 million people worldwide. The growing burden of survivorship is substantial in terms of the complexity of long-term health effects and the number of people affected. Persistent symptoms have been reported in patients with both mild and severe acute COVID-19, including those admitted to the intensive care unit (ICU). Early reports on the post-acute sequelae of SARS-CoV-2 infection (PASC) indicate that fatigue, dyspnoea, cough, headache, loss of taste or smell, and cognitive or mental health impairments are among the most common symptoms. These complex, multifactorial impairments across the domains of physical, cognitive, and mental health require a coordinated, multidisciplinary approach to management. Decades of research on the multifaceted needs of and models of care for patients with post-intensive care syndrome provide a framework for the development of PASC clinics to address the immediate needs of both hospitalised and non-hospitalised survivors of COVID-19. Such clinics could also provide a platform for rigorous research into the natural history of PASC and the potential benefits of therapeutic interventions.

Item Type:Articles
Additional Information:Dr. Parker is funded by an NIH/NHLBI award (K23HL138206). Dr. Turnbull is funded by an NIH early career development award (K01HL141637). Dr. Brigham is funded by an NIH early career development award (K23ES029105).
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Parker, Dr Anne and McPeake, Dr Jo
Authors: Parker, A. M., Brigham, E., Connolly, B., McPeake, J., Agranovich, A. V., Kenes, M. T., Casey, K., Reynolds, C., Schmidt, K. F.R., Kim, S. Y., Kaplin, A., Sevin, C. M., Brodsky, M. B., and Turnbull, A. E.
College/School:College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing > Nursing and Health Care
Journal Name:Lancet Respiratory Medicine
Publisher:The Lancet Publishing Group
ISSN:2213-2600
ISSN (Online):2213-2619
Published Online:19 October 2021
Copyright Holders:Copyright © 2021 Elsevier Ltd.
First Published:First published in Lancet Respiratory Medicine 9(11):1328-1341
Publisher Policy:Reproduced in accordance with the publisher copyright policy

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
307748Improving health and social care integration delivery in the acute care environmentJoanne McPeakeUniversity of Cambridge (HEI-CAMB)RG88620HW - MRC/CSO Social and Public Health Sciences Unit