Thrombophilia and maternal mortality: risk factors and preventive approaches

Nelson, S.M. and Greer, I.A. (2007) Thrombophilia and maternal mortality: risk factors and preventive approaches. Expert Review of Obstetrics and Gynaecology, July;2(4), pp. 477-488. (doi:10.1586/17474108.2.4.477)

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Abstract

Pregnancy-associated venous thromboembolism continues to be a significant cause of maternal mortality and morbidity. Unfortunately, many of these deaths could be prevented by optimal prophylaxis and management. This review describes recent developments in the understanding of the pathophysiology of the disease processes and the contribution that thrombophilia makes. Potential strategies for identification of women at high risk and current and future therapeutic strategies for the prevention of venous thrombosis in pregnancy are also discussed.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Nelson, Professor Scott and Greer, Prof Ian
Authors: Nelson, S.M., and Greer, I.A.
College/School:College of Medical Veterinary and Life Sciences
Journal Name:Expert Review of Obstetrics and Gynaecology

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