A comparison of enteropathogenic and enterohaemorrhagic Escherichia coli pathogenesis

Spears, K. J., Roe, A. and Gally, D. L. (2006) A comparison of enteropathogenic and enterohaemorrhagic Escherichia coli pathogenesis. FEMS Microbiology Letters, 255(2), pp. 187-202. (doi: 10.1111/j.1574-6968.2006.00119.x)

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Abstract

This review covers enteropathogenic <i>Escherichia coli</i> (EPEC) and enterohaemorrhagic <i>E. coli</i> (EHEC) infections, focusing on differences in their virulence factors and regulation. While Shiga-toxin expression from integrated bacteriophages sets EHEC apart from EPEC, EHEC infections often originate from asymptomatic carriage in ruminants whereas human EPEC are considered to be overt pathogens and more host-restricted. In part, these differences reflect variation in adhesin repertoire, type III-secreted effectors and the way in which these factors are regulated.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Roe, Professor Andrew
Authors: Spears, K. J., Roe, A., and Gally, D. L.
College/School:College of Medical Veterinary and Life Sciences
College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:FEMS Microbiology Letters
Publisher:Wiley
ISSN:0378-1097
ISSN (Online):1574-6968
Published Online:31 January 2006

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