Hammarton, T. C., Monnerat, S. and Mottram, J. C. (2007) Cytokinesis in trypanosomatids. Current Opinion in Microbiology, 10(6), pp. 520-527. (doi: 10.1016/j.mib.2007.10.005)
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Publisher's URL: http://dx.doi.org/10.1016/j.mib.2007.10.005
Abstract
The process of cytokinesis, where the cytoplasm of one cell is divided to produce two daughter cells, is intricate in trypanosomatids because of the requirement to replicate and segregate a number of single copy organelles, including the nucleus, kinetoplast, Golgi apparatus, and flagellum. Identifying regulators of the three stages of cytokinesis, initiation, furrow ingression, and abscission is complicated by the fact that cell division in trypanosomatids is easily perturbed and aberrant cells are readily produced during functional characterization of gene products. In this review, we discuss direct and indirect effects on cytokinesis, using Trypanosoma brucei as a model.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Hammarton, Dr Tansy and Monnerat, Dr Severine and Mottram, Professor Jeremy |
Authors: | Hammarton, T. C., Monnerat, S., and Mottram, J. C. |
College/School: | College of Medical Veterinary and Life Sciences College of Medical Veterinary and Life Sciences > School of Infection & Immunity |
Journal Name: | Current Opinion in Microbiology |
Publisher: | Elsevier |
ISSN: | 1369-5274 |
ISSN (Online): | 1879-0364 |
Published Online: | 26 November 2007 |
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