mSphere of influence: an army marching on its stomach-malaria parasites sense and subvert host nutrition

Harding, C. R. (2021) mSphere of influence: an army marching on its stomach-malaria parasites sense and subvert host nutrition. mSphere, 6(2), e00210-21. (doi: 10.1128/mSphere.00210-21) (PMID:33853872) (PMCID:PMC8546697)

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Abstract

Clare Harding works on the metal biology of the parasite In this mSphere of Influence article, she reflects on how two papers from the laboratory of Maria Mota, "Host-mediated regulation of superinfection in malaria" by Portugal et al. (S. Portugal, C. Carret, M. Recker, A. E. Armitage, et al., Nat Med 17:732-737, 2011, https://doi.org/10.1038/nm.2368) and "Nutrient sensing modulates malaria parasite virulence" by Mancio-Silva et al. (L. Mancio-Silva, K. Slavic, M. T. Grilo Ruivo, A. R. Grosso, et al., Nature 547:213-216, 2017, https://doi.org/10.1038/nature23009), made an impact on her understanding of host-pathogen interactions by examining the complex interplay between parasites and their hosts' nutritional status.

Item Type:Articles
Keywords:Apicomplexan parasites, immunity, malaria, nutrition.
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Harding, Dr Clare
Authors: Harding, C. R.
College/School:College of Medical Veterinary and Life Sciences > School of Infection & Immunity
Journal Name:mSphere
Publisher:American Society for Microbiology
ISSN:2379-5042
ISSN (Online):2379-5042
Published Online:14 April 2021
Copyright Holders:Copyright © 2021 Harding
First Published:First published in mSphere 6(2): e00210-21
Publisher Policy:Reproduced under a Creative Commons License

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
304336Iron usage in the eukaryotic parasite Toxoplasma gondiiClare HardingWellcome Trust (WELLCOTR)213455/Z/18/ZIII - Parasitology