Ryan, K. , Phillips, A. and Vousden, K. (2001) Regulation and function of the p53 tumor suppressor protein. Current Opinion in Cell Biology, 13(3), pp. 332-337. (doi: 10.1016/S0955-0674(00)00216-7)
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Abstract
Loss of the p53 tumor suppressor pathway contributes to the development of most human cancers. p53 is a nuclear protein that functions as a regulator of transcription. Significant advances have been made recently in our understanding of how p53 function is regulated and the mechanisms by which p53 mediates its effects.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Ryan, Professor Kevin and Vousden, Karen |
| Authors: | Ryan, K., Phillips, A., and Vousden, K. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Cancer Sciences |
| Journal Name: | Current Opinion in Cell Biology |
| ISSN: | 0955-0674 |
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