Caldwell, S. T. , O'Byrne, S., Wilson, C., Cvetko, F., Murphy, M. P., McCarron, J. G. and Hartley, R. C. (2021) Photoactivated release of membrane impermeant sulfonates inside cells. Chemical Communications, 57(32), pp. 3917-3920. (doi: 10.1039/D0CC07713E) (PMID:33871501) (PMCID:PMC7611313)
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Abstract
Photouncaging delivers compounds with high spatial and temporal control to induce or inhibit biological processes but the released compounds may diffuse out. We here demonstrate that sulfonate anions can be photocaged so that a membrane impermeable compound can enter cells, be uncaged by photoirradiation and trapped within the cell.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Caldwell, Dr Stuart and O'Byrne, Mr Sean and Hartley, Professor Richard |
Authors: | Caldwell, S. T., O'Byrne, S., Wilson, C., Cvetko, F., Murphy, M. P., McCarron, J. G., and Hartley, R. C. |
College/School: | College of Science and Engineering > School of Chemistry |
Journal Name: | Chemical Communications |
Publisher: | Royal Society of Chemistry |
ISSN: | 1359-7345 |
ISSN (Online): | 1364-548X |
Published Online: | 12 March 2021 |
Copyright Holders: | Copyright © 2021 The Authors |
First Published: | First published in Chemical Communications 57(32): 3917-3920 |
Publisher Policy: | Reproduced under a Creative Commons licence |
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