Kar, S. , Ghosh, U., Maiti, T. K. and Chakraborty, S. (2015) Haemoglobin content modulated deformation dynamics of red blood cells on a compact disc. Lab on a Chip, 15(24), pp. 4571-4577. (doi: 10.1039/C5LC00968E) (PMID:26502076)
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Abstract
We investigate the deformation characteristics of red blood cells (RBCs) on a rotating compact disc platform. Our study brings out the interplay between haemoglobin content and RBC deformability in a centrifugally actuated microfluidic environment. We reveal that RBC deformations follow the similar trend of principal stress distributed throughout the radial direction, rendering an insight into the mechano-physical processes involved. This study can be used as a diagnostic marker to determine haematological disorders in diseased blood samples tested on compact disc based microfluidic platforms.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Kar, Dr Shantimoy |
| Authors: | Kar, S., Ghosh, U., Maiti, T. K., and Chakraborty, S. |
| College/School: | College of Science and Engineering > School of Engineering > Biomedical Engineering |
| Journal Name: | Lab on a Chip |
| Publisher: | Royal Society of Chemistry |
| ISSN: | 1473-0197 |
| ISSN (Online): | 1473-0189 |
| Published Online: | 12 October 2015 |
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