The effect of exercise on quality of life and activities of daily life in frail older adults: a systematic review of randomised control trials

Campbell, E. , Petermann-Rocha, F., Welsh, P. , Celis-Morales, C. , Pell, J. P. , Ho, F. K. and Gray, S. R. (2021) The effect of exercise on quality of life and activities of daily life in frail older adults: a systematic review of randomised control trials. Experimental Gerontology, 147, 111287. (doi: 10.1016/j.exger.2021.111287) (PMID:33609689)

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Abstract

While the positive effects of exercise on frailty are well documented, the effect of exercise on quality of life (QoL) and activities of daily living (ADL) in frail older adults remains less certain. Therefore, this paper aimed to systematically review the literature investigating the effect of exercise on QoL and ADL in this group. Embase, MEDLINE, CENTRAL, PEDro and Web of Science Core Collections were searched systematically using relevant MeSH terms. The inclusion criteria were: controlled trial design, published in English, population included frail older adults, frailty measured quantitatively, interventions that included exercise, and QoL or ADL measurements (PROSPERO: CRD42018106173). After screening, 15 studies were eligible for inclusion in the qualitative synthesis (total n: 2467; mean age range: 70–85 years). There was a positive effect on QoL or ADL measures in 10 out of the 15 studies. QoL and ADLs only improved in studies that also reported improved physical outcomes. These results reflect the multi-factoral nature of frailty and how physical capability and QoL are interlinked. Heterogeneity precluded formal meta-analysis. Future trials in frail older adults should focus on interventions that include exercise, measure physical outcomes and use consistent study design to enable meta-analysis to be conducted.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Petermann Rocha, Fanny and Pell, Professor Jill and Celis, Dr Carlos and Gray, Dr Stuart and Ho, Dr Frederick and Welsh, Dr Paul and Campbell, Mr Evan
Authors: Campbell, E., Petermann-Rocha, F., Welsh, P., Celis-Morales, C., Pell, J. P., Ho, F. K., and Gray, S. R.
College/School:College of Medical Veterinary and Life Sciences > Institute of Cardiovascular and Medical Sciences > Exercise Physiology/Sports Medicine
College of Medical Veterinary and Life Sciences > Institute of Health and Wellbeing > Public Health
Journal Name:Experimental Gerontology
Publisher:Elsevier
ISSN:0531-5565
ISSN (Online):1873-6815
Published Online:18 February 2021
Copyright Holders:Copyright © 2021 Elsevier Inc.
First Published:First published in Experimental Gerontology 147: 111287
Publisher Policy:Reproduced in accordance with the publisher copyright policy

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