Expression of CXCR4 on feline peripheral blood mononuclear cells: effect of feline immunodeficiency virus infection.

Willett, B.J., Cannon, C.A. and Hosie, M.J. (2003) Expression of CXCR4 on feline peripheral blood mononuclear cells: effect of feline immunodeficiency virus infection. Journal of Virology, 77(1), pp. 709-712. (doi: 10.1128/JVI.77.1.709-712.2003)

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Publisher's URL: http://dx.doi.org/10.1128/JVI.77.1.709-712.2003

Abstract

CXCR4 expression on feline peripheral blood mononuclear cells (PBMC) was analyzed. While monocytes and B lymphocytes expressed CXCR4, no CXCR4 was detected on T lymphocytes, in stark contrast to the expression pattern on T lymphocytes from humans. In spite of the important role that CXCR4 plays in infection with feline immunodeficiency virus, expression on PBMC in vivo was unaffected by infection with either a primary or a cell culture-adapted virus strain.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Hosie, Professor Margaret and Willett, Professor Brian
Authors: Willett, B.J., Cannon, C.A., and Hosie, M.J.
Subjects:S Agriculture > SF Animal culture
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:Journal of Virology
Journal Abbr.:J. Virol.
ISSN:0022-538X
ISSN (Online):1098-5514
Copyright Holders:Copyright © 2003 American Society for Microbiology
First Published:First published in Journal of Virology 77(1):709-712
Publisher Policy:Reproduced in accordance with the copyright policy of the publisher.

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