Expression of CXCR4 on feline peripheral blood mononuclear cells: effect of feline immunodeficiency virus infection.

Willett, B.J., Cannon, C.A. and Hosie, M.J. (2003) Expression of CXCR4 on feline peripheral blood mononuclear cells: effect of feline immunodeficiency virus infection. Journal of Virology, 77(1), pp. 709-712. (doi: 10.1128/JVI.77.1.709-712.2003)

Abstract

CXCR4 expression on feline peripheral blood mononuclear cells (PBMC) was analyzed. While monocytes and B lymphocytes expressed CXCR4, no CXCR4 was detected on T lymphocytes, in stark contrast to the expression pattern on T lymphocytes from humans. In spite of the important role that CXCR4 plays in infection with feline immunodeficiency virus, expression on PBMC in vivo was unaffected by infection with either a primary or a cell culture-adapted virus strain.

• Item Type: Articles
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Hosie, Professor Margaret and Willett, Professor Brian
• Authors: Willett, B.J., Cannon, C.A., and Hosie, M.J.
• Subjects: S Agriculture > SF Animal culture
• College/School: College of Medical Veterinary and Life Sciences > School of Infection & Immunity; College of Medical Veterinary and Life Sciences > School of Infection & Immunity > Centre for Virus Research
• Journal Name: Journal of Virology
• Journal Abbr.: J. Virol.
• ISSN: 0022-538X
• ISSN (Online): 1098-5514
• Copyright Holders: Copyright © 2003 American Society for Microbiology
• First Published: First published in Journal of Virology 77(1):709-712
• Publisher Policy: Reproduced in accordance with the copyright policy of the publisher.