Therapeutic plasma exchange to mitigate flunixin meglumine overdose in a cria

Dixon, C. E. , Kelley, D., Froehlich, J. M., Gruntman, A., Oura, T., Mazan, M. R. and Labato, M. A. (2021) Therapeutic plasma exchange to mitigate flunixin meglumine overdose in a cria. Journal of Veterinary Emergency and Critical Care, 31(4), pp. 521-524. (doi: 10.1111/vec.13071) (PMID:33955631)

Abstract

Objective: To describe the use of therapeutic plasma exchange (TPE) in the treatment of flunixin meglumine overdose in a cria. Case Summary: A 3‐day‐old alpaca cria was diagnosed with ureteral obstruction and agenesis resulting in severe bilateral hydronephrosis. During hospitalization, the cria inadvertently received a flunixin meglumine overdose of >65 mg/kg. Here, we report the use of lipid emulsion and TPE to mitigate flunixin meglumine toxicosis. TPE appeared to prevent any flunixin‐induced kidney or gastrointestinal injury, even in a patient with congenital defects of the urinary tract. New Information Provided: This is the first report of the use of TPE in a cria.

• Item Type: Articles
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Dixon, Dr Claire
• Authors: Dixon, C. E., Kelley, D., Froehlich, J. M., Gruntman, A., Oura, T., Mazan, M. R., and Labato, M. A.
• College/School: College of Medical Veterinary and Life Sciences > School of Biodiversity, One Health & Veterinary Medicine
• Journal Name: Journal of Veterinary Emergency and Critical Care
• Publisher: Wiley
• ISSN: 1479-3261
• ISSN (Online): 1476-4431
• Published Online: 06 May 2021
• Copyright Holders: Copyright © 2021 The Authors
• First Published: First published in Journal of Veterinary Emergency and Critical Care 31(4): 521-524
• Publisher Policy: Reproduced under a Creative Commons licence