Polarization multi-parametric imaging method for the inspection of cervix cell

Liu, W., Xiong, J., Liu, J., Zhu, J., Hu, J., Hou, L. , Marsh, J. H. , Yie, M. and Liu, X. (2021) Polarization multi-parametric imaging method for the inspection of cervix cell. Optics Communications, 488, 126846. (doi: 10.1016/j.optcom.2021.126846)

Abstract

Accurate identification of the shape and texture properties of cervical cell nuclei and cytoplasm in the pap smear test is crucial for the diagnosis of cervical cancer. Fast and high-precision polarization modulation in the Polarization Indirect Microscopic Imaging (PIMI) is achieved by utilizing a liquid crystal polarization rotator. Imaging results of cervical cells show that the PIMI method can resolve detailed fine structural features of a cervical cell which are invisible in conventional microscopy. It also demonstrated the ability of embossed three-dimensional visualization as that in differential interference contrast microscopy (DIC), but with finer structural features.

• Item Type: Articles
• Additional Information: This work was supported by the National Major Scientific Instruments and Equipment Development Project under Grant No.61827814, Beijing Natural Science Foundation under Grant No.Z190018, the Fundamental Research Funds for the Central Universities under Grant No.30920010011 and the Ministry of Education collaborative project. It is also supported by the UK Engineering and Physical Sciences Research Council (Grant EP/R042578/1).
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Liu, Professor Xuefeng and Marsh, Professor John and Hou, Dr Lianping
• Authors: Liu, W., Xiong, J., Liu, J., Zhu, J., Hu, J., Hou, L., Marsh, J. H., Yie, M., and Liu, X.
• College/School: College of Science and Engineering > School of Engineering; College of Science and Engineering > School of Engineering > Electronics and Nanoscale Engineering
• Journal Name: Optics Communications
• Publisher: Elsevier
• ISSN: 0030-4018
• ISSN (Online): 1873-0310
• Published Online: 06 February 2021
• Copyright Holders: Copyright © 2021 Elsevier B.V.
• First Published: First published in Optics Communications 488:126846
• Publisher Policy: Reproduced in accordance with the copyright policy of the publisher

Project Code	Award No	Project Name	Principal Investigator	Funder's Name	Funder Ref	Lead Dept
302617		Optically controlled THz phased array antennas	John Marsh	Engineering and Physical Sciences Research Council (EPSRC)	EP/R042578/1	ENG - Electronics & Nanoscale Engineering