Polarization multi-parametric imaging method for the inspection of cervix cell

Liu, W., Xiong, J., Liu, J., Zhu, J., Hu, J., Hou, L. , Marsh, J. H. , Yie, M. and Liu, X. (2021) Polarization multi-parametric imaging method for the inspection of cervix cell. Optics Communications, 488, 126846. (doi: 10.1016/j.optcom.2021.126846)

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Abstract

Accurate identification of the shape and texture properties of cervical cell nuclei and cytoplasm in the pap smear test is crucial for the diagnosis of cervical cancer. Fast and high-precision polarization modulation in the Polarization Indirect Microscopic Imaging (PIMI) is achieved by utilizing a liquid crystal polarization rotator. Imaging results of cervical cells show that the PIMI method can resolve detailed fine structural features of a cervical cell which are invisible in conventional microscopy. It also demonstrated the ability of embossed three-dimensional visualization as that in differential interference contrast microscopy (DIC), but with finer structural features.

Item Type:Articles
Additional Information:This work was supported by the National Major Scientific Instruments and Equipment Development Project under Grant No.61827814, Beijing Natural Science Foundation under Grant No.Z190018, the Fundamental Research Funds for the Central Universities under Grant No.30920010011 and the Ministry of Education collaborative project. It is also supported by the UK Engineering and Physical Sciences Research Council (Grant EP/R042578/1).
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Liu, Professor Xuefeng and Marsh, Professor John and Hou, Dr Lianping
Authors: Liu, W., Xiong, J., Liu, J., Zhu, J., Hu, J., Hou, L., Marsh, J. H., Yie, M., and Liu, X.
College/School:College of Science and Engineering > School of Engineering
College of Science and Engineering > School of Engineering > Electronics and Nanoscale Engineering
Journal Name:Optics Communications
Publisher:Elsevier
ISSN:0030-4018
ISSN (Online):1873-0310
Published Online:06 February 2021
Copyright Holders:Copyright © 2021 Elsevier B.V.
First Published:First published in Optics Communications 488:126846
Publisher Policy:Reproduced in accordance with the copyright policy of the publisher

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
302617Optically controlled THz phased array antennasJohn MarshEngineering and Physical Sciences Research Council (EPSRC)EP/R042578/1ENG - Electronics & Nanoscale Engineering