Clinical experience with endothelin receptor antagonists in chronic heart failure

Seed, A., Love, M. P. and McMurray, J. J.V. (2001) Clinical experience with endothelin receptor antagonists in chronic heart failure. Heart Failure Reviews, 6(4), pp. 317-323. (doi: 10.1023/A:1011408425878) (PMID:11447306)

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Abstract

Both ETA selective and dual, ETA=B, receptor antagonists have favourable short- and longer-term haemodynamic actions in patients with acute and chronic heart failure. Their effect on neurohumoral measures is not yet fully determined. Two moderately large, medium-duration studies have examined the effect of dual ETA=B receptor antagonists on clinical status, reaching conflicting conclusions. One large scale, long-term, morbidity mortality evaluation is underway with bosentan.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:McMurray, Professor John
Authors: Seed, A., Love, M. P., and McMurray, J. J.V.
College/School:College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health
Journal Name:Heart Failure Reviews
Publisher:Springer
ISSN:1382-4147
ISSN (Online):1573-7322

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