Superficial vein thrombosis: incidence in association with pregnancy and prevalence of thrombophilic defects

McColl, M.D., Ramsay, J.E., Tait, R.C. , Walker, I.D., McCall, F., Conkie, J.A., Carty, M.J. and Greer, I.A. (1998) Superficial vein thrombosis: incidence in association with pregnancy and prevalence of thrombophilic defects. Thrombosis and Haemostasis, 79(4), pp. 741-742. (doi: 10.1055/s-0037-1615056) (PMID:9569184)

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Abstract

Superficial venous thrombotic (SVT) events are a feature of thrombophilic abnormalities, particularly those involving the protein C pathway. We have determined the incidence of SVT associated with pregnancy and the early postpartum period in a retrospective study involving 72 000 deliveries. Fourty-nine cases occurring in 47 individuals were recorded, with an overall incidence of 0.68/1000 deliveries (95% CI 0.48-0.88). None had a previous history of deep vein thrombosis or pulmonary embolism. Most events occurred in the early post-partum period (0.54/1000 deliveries). Twenty-four/fourty-seven were screened for established thrombophilic abnormalities, with only 1 abnormality detected (FVLeiden heterozygote). Thrombophilia may play a minor role in the aetiology of SVT associated with pregnancy, although a larger study is required to confirm this.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Tait, Dr Robert and McColl, Dr Mark and Walker, Prof Isobel and Ramsay, Dr Jane
Authors: McColl, M.D., Ramsay, J.E., Tait, R.C., Walker, I.D., McCall, F., Conkie, J.A., Carty, M.J., and Greer, I.A.
College/School:College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health
College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
Journal Name:Thrombosis and Haemostasis
Publisher:Georg Thieme
ISSN:0340-6245
ISSN (Online):2567-689X

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