The KRAS-BCAA-BCAT2 axis in PDAC development

Falcone, M. and Maddocks, O. D.K. (2020) The KRAS-BCAA-BCAT2 axis in PDAC development. Nature Cell Biology, 22(2), pp. 139-140. (doi: 10.1038/s41556-020-0467-2) (PMID:32029895)

[img] Text
227419.pdf - Accepted Version

765kB

Abstract

Understanding the metabolic rewiring of pancreatic ductal adenocarcinoma is an emerging strategy for identifying cancer-associated liabilities and improving treatment. A new study now elucidates the function of the transaminase BCAT2 in the early stages of tumor development, providing insights that could stimulate novel therapeutic strategies.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Falcone, Dr Mattia and Maddocks, Professor Oliver
Authors: Falcone, M., and Maddocks, O. D.K.
College/School:College of Medical Veterinary and Life Sciences > Institute of Cancer Sciences
Journal Name:Nature Cell Biology
Publisher:Nature Research
ISSN:1465-7392
ISSN (Online):1476-4679
Published Online:06 February 2020
Copyright Holders:Copyright © 2020 Springer Nature Limited
First Published:First published in Nature Cell Biology 22(2):139-140
Publisher Policy:Reproduced in accordance with the copyright policy of the publisher

University Staff: Request a correction | Enlighten Editors: Update this record