Falcone, M. and Maddocks, O. D.K. (2020) The KRAS-BCAA-BCAT2 axis in PDAC development. Nature Cell Biology, 22(2), pp. 139-140. (doi: 10.1038/s41556-020-0467-2) (PMID:32029895)
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Abstract
Understanding the metabolic rewiring of pancreatic ductal adenocarcinoma is an emerging strategy for identifying cancer-associated liabilities and improving treatment. A new study now elucidates the function of the transaminase BCAT2 in the early stages of tumor development, providing insights that could stimulate novel therapeutic strategies.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Falcone, Dr Mattia and Maddocks, Professor Oliver |
| Authors: | Falcone, M., and Maddocks, O. D.K. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Cancer Sciences |
| Journal Name: | Nature Cell Biology |
| Publisher: | Nature Research |
| ISSN: | 1465-7392 |
| ISSN (Online): | 1476-4679 |
| Published Online: | 06 February 2020 |
| Copyright Holders: | Copyright © 2020 Springer Nature Limited |
| First Published: | First published in Nature Cell Biology 22(2):139-140 |
| Publisher Policy: | Reproduced in accordance with the copyright policy of the publisher |
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