Abp1p and cortactin, new “hand-holds” for actin

Olazabal, I. M. and Machesky, L. M. (2001) Abp1p and cortactin, new “hand-holds” for actin. Journal of Cell Biology, 154(4), pp. 679-682. (doi: 10.1083/jcb.200105061) (PMID:11514584) (PMCID:PMC2196464)

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Recently, two new ligands of the Arp2/3 complex have been described that may shed light on the way cells organize complex networks of actin in response to signals. Abp1p, a yeast protein involved in endocytosis, and cortactin, a mammalian src substrate, both enhance the ability of the Arp2/3 complex to assemble branched actin filament networks.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Machesky, Professor Laura
Authors: Olazabal, I. M., and Machesky, L. M.
College/School:College of Medical Veterinary and Life Sciences > School of Cancer Sciences
Journal Name:Journal of Cell Biology
Publisher:Rockefeller University Press
ISSN (Online):1540-8140

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