Radford, J. , Lyons, A. , Tonolini, F. and Faccio, D. (2020) Role of late photons in diffuse optical imaging. Optics Express, 28(20), pp. 29486-29495. (doi: 10.1364/OE.402503)
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Abstract
The ability to image through turbid media, such as organic tissues, is a highly attractive prospect for biological and medical imaging. This is challenging, however, due to the highly scattering properties of tissues which scramble the image information. The earliest photons that arrive at the detector are often associated with ballistic transmission, whilst the later photons are associated with complex paths due to multiple independent scattering events and are therefore typically considered to be detrimental to the final image formation process. In this work, we report on the importance of these highly diffuse, “late” photons for computational time-of-flight diffuse optical imaging. In thick scattering materials, >80 transport mean free paths, we provide evidence that including late photons in the inverse retrieval enhances the image reconstruction quality. We also show that the late photons alone have sufficient information to retrieve images of a similar quality to early photon gated data. This result emphasises the importance in the strongly diffusive regime of fully time-resolved imaging techniques.
| Item Type: | Articles |
|---|---|
| Additional Information: | The authors acknowledge funding from EPSRC (UK, grant no. EP/T00097X/1). DF is supported by the Royal Academy of Engineering under the Chairs in Emerging Technologies scheme. JR is supported by the EPSRC Centre for Doctoral Training in Intelligent Sensing and Measurement, Grant Number EP/L016753/1. FT is supported by Amazon and EPSRC grant EP/M01326X/1. |
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Faccio, Professor Daniele and Tonolini, Francesco and Radford, Jack and Lyons, Dr Ashley |
| Authors: | Radford, J., Lyons, A., Tonolini, F., and Faccio, D. |
| College/School: | College of Science and Engineering College of Science and Engineering > School of Physics and Astronomy |
| Journal Name: | Optics Express |
| Publisher: | Optical Society of America |
| ISSN: | 1094-4087 |
| ISSN (Online): | 1094-4087 |
| Copyright Holders: | Copyright © 2020 Optical Society of America |
| First Published: | First published in Optics Express 28(20:29486-29495 |
| Publisher Policy: | Reproduced under a Creative Commons License |
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