Lymphocyte activation after a high-intensity street dance class

Borges, L., Gorjão, R., Gray, S. , Martins, T. R., Santos, V. C., Momesso, C. M., Pithon-Curi, T. C. and Hatanaka, E. (2020) Lymphocyte activation after a high-intensity street dance class. PLoS ONE, 15(9), e0239516. (doi: 10.1371/journal.pone.0239516) (PMID:32956398) (PMCID:PMC7505442)

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Abstract

Intense dance training leads to inflammation, which may impair the health and performance of the practitioners. Herein, we evaluate the effect of a single street dancing class on the profile of muscle enzymes, lymphocyte activation, and cell surface CD62L expression. We also investigated the correlation between muscle enzymes, adhesion molecules, and lymphocyte activation in dancers. Fifteen male participants (mean ± standard error: age 22.4 ± 1.08 years, body mass index 24.8 ± 0.69 kg/m2, body fat 12.3 ± 1.52%), who were amateur dancers, had blood samples collected previously and subsequent to a high-intensity street dance class. After the class, dancers showed an increase in total lymphocyte count (2.0-fold), creatine kinase (CK)-NAC (4.87%), and CK-MB (3.36%). We also observed a decrease (2.5-fold) in reactive oxygen species (ROS) produced by lymphocytes, under phorbol myristate acetate-stimulated environments. Following the dance class, CD62L expression in lymphocytes decreased (51.42%), while there was a negative correlation between the intensity of the exercise and CD62L expression (r = -0.73; p = 0.01). Lymphocytes were less responsive to stimuli after a single bout of street dancing, indicating transient immunosuppression.

Item Type:Articles
Additional Information:This research was supported by the Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) under Grant [2011/21441-0 and 2014/21185-1] (EH); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) under Grant [306041/2011-1 and 308700/2017-1] (EH); and the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) under Grant [88882.314890/2013-01] (LB).
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Gray, Dr Stuart
Creator Roles:
Gray, S.Visualization
Authors: Borges, L., Gorjão, R., Gray, S., Martins, T. R., Santos, V. C., Momesso, C. M., Pithon-Curi, T. C., and Hatanaka, E.
College/School:College of Medical Veterinary and Life Sciences > Institute of Cardiovascular and Medical Sciences
Journal Name:PLoS ONE
Publisher:Public Library of Science
ISSN:1932-6203
ISSN (Online):1932-6203
Copyright Holders:Copyright © 2020 The Authors
First Published:First published in PLoS ONE 15(9):e0239516
Publisher Policy:Reproduced under a Creative Commons License

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