Harnessing technology and portability to conduct molecular epidemiology of endemic pathogens in resource-limited settings

Faust, C. L. et al. (2021) Harnessing technology and portability to conduct molecular epidemiology of endemic pathogens in resource-limited settings. Transactions of the Royal Society of Tropical Medicine and Hygiene, 115(1), pp. 3-5. (doi: 10.1093/trstmh/traa086) (PMID:32945867) (PMCID:PMC7788292)

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Abstract

Improvements in genetic and genomic technology have enabled field-deployable molecular laboratories and these have been deployed in a variety of epidemics that capture headlines. In this editorial, we highlight the importance of building physical and personnel capacity in low and middle income countries to deploy these technologies to improve diagnostics, understand transmission dynamics and provide feedback to endemic communities on actionable timelines. We describe our experiences with molecular field research on schistosomiasis, trypanosomiasis and rabies and urge the wider tropical medicine community to embrace these methods and help build capacity to benefit communities affected by endemic infectious diseases.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Ryan, Miss Mary and Brunker, Dr Kirstyn and Lamberton, Dr Poppy and Faust, Christina
Authors: Faust, C. L., Brunker, K., Ajambo, D., Ryan, M., Moses, A., Rowel, C., Wangoola, R. M., Wampande, E. M., Guma, A., Adriko, M., Lamberton, P. H.L., Tukahebwa, E. M., Mugenyi, A., and Waiswa, C.
College/School:College of Medical Veterinary and Life Sciences > Institute of Biodiversity Animal Health and Comparative Medicine
Journal Name:Transactions of the Royal Society of Tropical Medicine and Hygiene
Publisher:Oxford University Press
ISSN:0035-9203
ISSN (Online):1878-3503
Published Online:18 September 2020
Copyright Holders:Copyright © 2020 The Authors
First Published:First published in Transactions of the Royal Society of Tropical Medicine and Hygiene 115(1):3–5
Publisher Policy:Reproduced under a Creative Commons Licence

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
301620The Science of Rabies EliminationKatie HampsonWellcome Trust (WELLCOTR)207569/Z/17/ZInstitute of Biodiversity, Animal Health and Comparative Medicine
173707Institutional Strategic Support Fund (2016)Anna DominiczakWellcome Trust (WELLCOTR)204820/Z/16/ZInstitute of Cardiovascular & Medical Sciences
300909Moving from laboratory-based to real-time genomic surveillance of canine rabies virus in the field.Kirstyn BrunkerRoyal Society of Tropical Medicine and Hygiene (RSTMH)GR000892Institute of Biodiversity, Animal Health and Comparative Medicine
306188EPSRC-GCRF Global Impact Accelerator Account 2018 UofGJonathan CooperEngineering and Physical Sciences Research Council (EPSRC)EP/S51584X/1Research and Innovation Services
172876SCHISTO-PERSISTPoppy LambertonEuropean Research Council (ERC)680088Institute of Biodiversity, Animal Health and Comparative Medicine