De Venuto, D., Annese, V. F. , Mezzina, G., Scioscia, F., Ruta, M., Di Sciascio, E. and Sangiovanni Vincentelli, A. (2018) A Mobile Health System for Neurocognitive Impairment Evaluation Based on P300 Detection. ACM Transactions on Cyber-Physical Systems, 2(4), 31. (doi: 10.1145/3140236)
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Abstract
A new mobile healthcare system for neuro-cognitive function monitoring and treatment is presented. The architecture of the system features sensors to measure the brain potential, localized data analysis and filtering, and in-cloud distribution to specialized medical personnel. As such, it presents tradeoffs typical of other cyber-physical systems, where hardware, algorithms, and software implementations have to come together in a coherent fashion. The system is based on spatio-temporal detection and characterization of a specific brain potential called P300. The diagnosis of cognitive deficit is achieved by analyzing the data collected by the system with a new algorithm called tuned-Residue Iteration Decomposition (t-RIDE). The system has been tested on 17 subjects (n = 12 healthy, n = 3 mildly cognitive impaired, and n = 2 with Alzheimer's disease involved in three different cognitive tasks with increasing difficulty. The system allows fast diagnosis of cognitive deficit, including mild and heavy cognitive impairment: t-RIDE convergence is achieved in 79 iterations (i.e., 1.95s), yielding an 80% accuracy in P300 amplitude evaluation with only 13 trials on a single EEG channel.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Annese, Dr Valerio |
Authors: | De Venuto, D., Annese, V. F., Mezzina, G., Scioscia, F., Ruta, M., Di Sciascio, E., and Sangiovanni Vincentelli, A. |
College/School: | College of Science and Engineering > School of Engineering > Electronics and Nanoscale Engineering |
Journal Name: | ACM Transactions on Cyber-Physical Systems |
Publisher: | ACM |
ISSN: | 2378-962X |
ISSN (Online): | 2378-9638 |
Published Online: | 01 July 2018 |
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