Heath, F., Hurley, S. A., Johansen-Berg, H. and Sampaio-Baptista, C. (2018) Advances in noninvasive myelin imaging. Developmental Neurobiology, 78(2), pp. 136-151. (doi: 10.1002/dneu.22552) (PMID:29082667) (PMCID:PMC5813152)
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Abstract
Myelin is important for the normal development and healthy function of the nervous system. Recent developments in MRI acquisition and tissue modeling aim to provide a better characterization and more specific markers for myelin. This allows for specific monitoring of myelination longitudinally and noninvasively in the healthy brain as well as assessment of treatment and intervention efficacy. Here, we offer a nontechnical review of MRI techniques developed to specifically monitor myelin such as magnetization transfer (MT) and myelin water imaging (MWI). We further summarize recent studies that employ these methods to measure myelin in relation to development and aging, learning and experience, and neuropathology and psychiatric disorders.
Item Type: | Articles |
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Additional Information: | This work was supported by Wellcome Principal Research Fellowship to HJB (WT110027/Z/15/Z). |
Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Sampaio Baptista, Dr Cassandra |
Authors: | Heath, F., Hurley, S. A., Johansen-Berg, H., and Sampaio-Baptista, C. |
College/School: | College of Medical Veterinary and Life Sciences > School of Psychology & Neuroscience |
Journal Name: | Developmental Neurobiology |
Publisher: | Wiley |
ISSN: | 1932-8451 |
ISSN (Online): | 1932-846X |
Published Online: | 30 October 2017 |
Copyright Holders: | Copyright © 2017 The Authors |
First Published: | First published in Developmental Neurobiology 78(2): 136-151 |
Publisher Policy: | Reproduced under a Creative Commons License |
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