Laser scanning cytometry: understanding the immune system in situ

Harnett, M. M. (2007) Laser scanning cytometry: understanding the immune system in situ. Nature Reviews Immunology, 7(11), pp. 897-904. (doi:10.1038/nri2188)

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Publisher's URL: http://dx.doi.org/10.1038/nri2188

Abstract

Flow cytometry allows quantitative analysis of the identity and effector function of individual cells. However, it cannot provide information on cellular responses that occur within physiological tissue microenvironments. Laser scanning cytometry is an emerging technology that allows imaging and quantitative analysis of individual cells in tissues in situ. This article describes the technology and its potential for delineating the molecular and cellular events underpinning the immune response in health and disease.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Harnett, Professor Margaret
Authors: Harnett, M. M.
College/School:College of Medical Veterinary and Life Sciences
College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:Nature Reviews Immunology
Publisher:Nature Publishing Group
ISSN:1474-1733
ISSN (Online):1474-1741
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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
410691T cell signalling events in vivo during the induction of immunity and toleranceMargaret HarnettMedical Research Council (MRC)G0500580Infection Immunity and Inflammation Medicine