Genomics of hypertension

Padmanabhan, S. , Aman, A. and Dominiczak, A. F. (2019) Genomics of hypertension. In: Touyz, R.M. and Delles, C. (eds.) Textbook of Vascular Medicine. Springer, pp. 171-181. ISBN 9783030164805 (doi:10.1007/978-3-030-16481-2_16)

Full text not currently available from Enlighten.

Abstract

Blood pressure genomics is among the most challenging of research fields in cardiovascular medicine. The genome-wide association studies era resulted in an unparalleled burst of discovery greatly advancing our understanding of the genetic architecture of blood pressure. In this chapter we provide an introduction to complex trait genetics and describe the various monogenic syndromes of hypertension and hypotension followed by recent insights from genome-wide association studies of the polygenic blood pressure trait and hypertension.

Item Type:Book Sections
Additional Information:Online ISBN: 9783030164812.
Status:Published
Glasgow Author(s) Enlighten ID:Padmanabhan, Professor Sandosh and Dominiczak, Professor Anna and Aman, Alisha
Authors: Padmanabhan, S., Aman, A., and Dominiczak, A. F.
College/School:College of Medical Veterinary and Life Sciences > Institute of Cardiovascular and Medical Sciences
Publisher:Springer
ISBN:9783030164805
Published Online:03 August 2019

University Staff: Request a correction | Enlighten Editors: Update this record