Genomics of hypertension

Padmanabhan, S. , Aman, A. and Dominiczak, A. F. (2019) Genomics of hypertension. In: Touyz, R.M. and Delles, C. (eds.) Textbook of Vascular Medicine. Springer, pp. 171-181. ISBN 9783030164805 (doi: 10.1007/978-3-030-16481-2_16)

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Blood pressure genomics is among the most challenging of research fields in cardiovascular medicine. The genome-wide association studies era resulted in an unparalleled burst of discovery greatly advancing our understanding of the genetic architecture of blood pressure. In this chapter we provide an introduction to complex trait genetics and describe the various monogenic syndromes of hypertension and hypotension followed by recent insights from genome-wide association studies of the polygenic blood pressure trait and hypertension.

Item Type:Book Sections
Additional Information:Online ISBN: 9783030164812.
Glasgow Author(s) Enlighten ID:Aman, Alisha and Padmanabhan, Professor Sandosh and Dominiczak, Professor Anna
Authors: Padmanabhan, S., Aman, A., and Dominiczak, A. F.
College/School:College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health
College of Medical Veterinary and Life Sciences
Published Online:03 August 2019

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