Dietary strategies for maintenance of clinical remission in inflammatory bowel diseases: Are we there yet?

Gkikas, K., Gerasimidis, K. , Milling, S. , Ijaz, U. Z. , Hansen, R. and Russell, R. (2020) Dietary strategies for maintenance of clinical remission in inflammatory bowel diseases: Are we there yet? Nutrients, 12(7), 2018. (doi: 10.3390/nu12072018) (PMID:32645980) (PMCID:PMC7400838)

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Abstract

The etiopathogenesis of Inflammatory bowel disease (IBD) is a result of a complex interaction between host immune response, the gut microbiome and environmental factors, such as diet. Although scientific advances, with the use of biological medications, have revolutionized IBD treatment, the challenge for maintaining clinical remission and delaying clinical relapse is still present. As exclusive enteral nutrition has become a well-established treatment for the induction of remission in pediatric Crohn’s disease, the scientific interest regarding diet in IBD is now focused on the development of follow-on dietary strategies, which aim to suppress colonic inflammation and delay a disease flare. The objective of this review is to present an extensive overview of the dietary strategies, which have been used in the literature to maintain clinical remission in both Crohn’s disease and Ulcerative colitis, and the evidence surrounding the association of dietary components with clinical relapse. We also aim to provide study-related recommendations to be encompassed in future research studies aiming to investigate the role of diet during remission periods in IBD.

Item Type:Articles
Additional Information:Funding: The studentship of K.G. (Konstantinos Gkikas) is partly funded by Nestle Health Science.
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Hansen, Dr Richard and Russell, Dr Richard and Gkikas, Konstantinos and Milling, Professor Simon and Gerasimidis, Professor Konstantinos and Ijaz, Dr Umer
Authors: Gkikas, K., Gerasimidis, K., Milling, S., Ijaz, U. Z., Hansen, R., and Russell, R.
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
College of Science and Engineering > School of Engineering > Infrastructure and Environment
Journal Name:Nutrients
Publisher:MDPI
ISSN:2072-6643
ISSN (Online):2072-6643
Copyright Holders:Copyright © 2020 The Authors
First Published:First published in Nutrients 12:2018
Publisher Policy:Reproduced under a Creative Commons Licence

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