Protocol for a randomised controlled trial to investigate the effect of home and gym-based resistance exercise training on glycaemic control, body composition and muscle strength

Al Ozairi, E. et al. (2020) Protocol for a randomised controlled trial to investigate the effect of home and gym-based resistance exercise training on glycaemic control, body composition and muscle strength. Trials, 21, 557. (doi: 10.1186/s13063-020-04480-2) (PMID:32571396) (PMCID:PMC7310149)

[img]
Preview
Text
217853.pdf - Published Version
Available under License Creative Commons Attribution.

763kB

Abstract

Background Resistance exercise is known to be effective in reducing glycated haemoglobin (HbA1c) in people with type 2 diabetes. However, studies, so far, have employed supervised resistance exercise in a laboratory or gym facility which limits the future translation of such exercise in to clinical practice and recommendations. Our primary aim, therefore, is to test the hypothesis, in a randomized controlled trial, that home-based resistance exercise training and gym-based resistance exercise training both reduce HbA1c levels in people with type 2 diabetes compared to control. We will also investigate the effects of home- and gym-based resistance exercise training on muscle strength and body composition. Methods The current study is a three-arm randomised controlled trial which will be conducted with 150 eligible people with type 2 diabetes to compare home-and gym-based resistance exercise training with usual care in Kuwait. The interventions will be delivered by exercise specialists and last for 32 weeks. The primary outcomes are HbA1c with secondary outcomes measuring muscle function, body composition, physical activity and quality of life. Discussion Ethical approval has been granted by the Dasman Diabetes Institute ethical review committee (RA/197/2019). Study findings will be disseminated through presentation at scientific conferences and in scientific journals.

Item Type:Articles
Additional Information:The study is funded by a grant from Monteral Medical International, Kuwait to University of Glasgow.
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Gray, Professor Cindy and Gray, Dr Stuart and Gill, Professor Jason and Welsh, Dr Paul and Sattar, Professor Naveed
Authors: Al Ozairi, E., Alsaeed, D., Taliping, D., Jalali, M., El Samad, A., Mashankar, A., Taghadom, E., Guess, N., Gill, J. M.R., Sattar, N., Gray, C., Welsh, P., and Gray, S. R.
College/School:College of Medical Veterinary and Life Sciences > Institute of Cardiovascular and Medical Sciences
College of Medical Veterinary and Life Sciences > Institute of Health and Wellbeing > Social Scientists working in Health and Wellbeing
Journal Name:Trials
Publisher:BioMed Central
ISSN:1745-6215
ISSN (Online):1745-6215
Copyright Holders:Copyright © 2020 The Authors
First Published:First published in Trials 21:557
Publisher Policy:Reproduced under a Creative Commons licence

University Staff: Request a correction | Enlighten Editors: Update this record