Programming properties of transient hydrogels by an enzymatic reaction

Panja, S. , Bohacova, K., Dietrich, B. and Adams, D. J. (2020) Programming properties of transient hydrogels by an enzymatic reaction. Nanoscale, 12(24), pp. 12840-12848. (doi: 10.1039/D0NR03012K) (PMID:32515773)

[img] Text
217283.pdf - Published Version
Available under License Creative Commons Attribution.



Supramolecular gels are usually stable in time as they are formed under thermodynamic equilibrium or at least in a deep well of a kinetically trapped state. However, artificial construction of kinetically controlled transient supramolecular gels is an interesting challenge. In these systems, usually a kinetically trapped transient aggregate is formed by active building blocks that leads to gelation; the gel then typically returns to the solution state. In this work, we show that such transient aggregation can occur by successive formation of two distinctly different kinetically controlled metastable states. Control over the first metastable state allows us to achieve significant control over the stability and properties of the second metastable state.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Dietrich, Bart and Adams, Dave and Panja, Dr Santanu
Authors: Panja, S., Bohacova, K., Dietrich, B., and Adams, D. J.
College/School:College of Science and Engineering > School of Chemistry
Journal Name:Nanoscale
Publisher:Royal Society of Chemistry
ISSN (Online):2040-3372
Published Online:03 June 2020
Copyright Holders:Copyright © 2020 The Royal Society of Chemistry
First Published:First published in Nanoscale 12(24): 12840-12848
Publisher Policy:Reproduced under a Creative Commons License

University Staff: Request a correction | Enlighten Editors: Update this record

Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
174004Multicomponent Supramolecular HydrogelsDave AdamsEngineering and Physical Sciences Research Council (EPSRC)EP/L021978/2Chemistry