Recent advances in synthetic methods for radioiodination

Dubost, E., Mcerlain, H., Babin, V., Sutherland, A. and Cailly, T. (2020) Recent advances in synthetic methods for radioiodination. Journal of Organic Chemistry, 85(13), pp. 8300-8310. (doi: 10.1021/acs.joc.0c00644) (PMID:32369696)

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Organic compounds bearing radioisotopes of iodine are widely used for biological research, diagnostic imaging, and radiotherapy. Early reported synthetic methods for the incorporation of radioiodine have generally involved high temperature reactions or strongly oxidizing conditions. To overcome these limitations and to cope with the demand for novel radioiodinated probes, there has been a surge in the development of new synthetic methodology for radioiodination. This synopsis describes the key transformations developed recently.

Item Type:Articles
Additional Information:The authors are grateful for financial support provided by the Regional Council of Normandy, FEDER, Crunch Network, la Ligue Contre le Cancer, the ARC foundation, the University of Caen, Carnot I2C, the French Ministry of Research, Dr. Ian Sword (studentship for H.M.), and the University of Glasgow.
Glasgow Author(s) Enlighten ID:Sutherland, Professor Andrew and Mcerlain, Miss Holly
Authors: Dubost, E., Mcerlain, H., Babin, V., Sutherland, A., and Cailly, T.
College/School:College of Science and Engineering > School of Chemistry
Journal Name:Journal of Organic Chemistry
Publisher:American Chemical Society
ISSN (Online):1520-6904
Published Online:13 May 2020
Copyright Holders:Copyright © 2020 The American Chemical Society
First Published:First published in Journal of Organic Chemistry 85(13): 8300-8310
Publisher Policy:Reproduced under the ACS Editor's Choice License

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