The impact of two-component sensorial network in staphylococcal speciation

Rapun-Araiz, B., Haag, A. F. , Solano, C. and Lasa, I. (2020) The impact of two-component sensorial network in staphylococcal speciation. Current Opinion in Microbiology, 55, pp. 40-47. (doi: 10.1016/j.mib.2020.02.004) (PMID:32199334)

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Abstract

Bacteria use two-component systems (TCSs) to sense and respond to their environments. Free-living bacteria usually contain dozens of TCSs, each of them responsible for sensing and responding to a different range of signals. Differences in the content of two-component systems are related with the capacity of the bacteria to colonize different niches or improve the efficiency to grow under the conditions of the existing niche. This review highlights differences in the TCS content between Staphylococcus aureus and Staphylococcus saprophyticus as a case study to exemplify how the ability to sense and respond to the environment is relevant for bacterial capacity to colonize and survive in/on different body surfaces.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Haag, Dr Andreas
Creator Roles:
Haag, A. F.Data curation, Investigation, Methodology, Writing – review and editing
Authors: Rapun-Araiz, B., Haag, A. F., Solano, C., and Lasa, I.
College/School:College of Medical Veterinary and Life Sciences > School of Infection & Immunity
Journal Name:Current Opinion in Microbiology
Publisher:Elsevier
ISSN:1369-5274
ISSN (Online):1879-0364
Copyright Holders:Copyright © 2020 The Authors
First Published:First published in Current Opinion in Microbiology 55: 40-47
Publisher Policy:Reproduced under a Creative Commons License

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
172321DUT-SignalJose R PenadesEuropean Research Council (ERC)670932Institute of Infection, Immunity & Inflammation
173676Investigating the regulation of Staphylococcus aureus environmental adaption for the identification of novel antibiotic targetsAndreas HaagTenovus Scotland (TENOVUS)Project S16/12Institute of Infection, Immunity & Inflammation