A comparative look at structural variation among RC-LH1 ‘core’ complexes present in anoxygenic phototrophic bacteria

Gardiner, A., Nguyen-Phan, T. C. and Cogdell, R. J. (2020) A comparative look at structural variation among RC-LH1 ‘core’ complexes present in anoxygenic phototrophic bacteria. Photosynthesis Research, (doi: 10.1007/s11120-020-00758-3) (PMID:32430765) (Early Online Publication)

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Abstract

All purple photosynthetic bacteria contain RC–LH1 ‘Core’ complexes. The structure of this complex from Rhodobacter sphaeroides, Rhodopseudomonas palustris and Thermochromatium tepidum has been solved using X-ray crystallography. Recently, the application of single particle cryo-EM has revolutionised structural biology and the structure of the RC–LH1 ‘Core’ complex from Blastochloris viridis has been solved using this technique, as well as the complex from the non-purple Chloroflexi species, Roseiflexus castenholzii. It is apparent that these structures are variations on a theme, although with a greater degree of structural diversity within them than previously thought. Furthermore, it has recently been discovered that the only phototrophic representative from the phylum Gemmatimonadetes, Gemmatimonas phototrophica, also contains a RC–LH1 ‘Core’ complex. At present only a low-resolution EM-projection map exists but this shows that the Gemmatimonas phototrophica complex contains a double LH1 ring. This short review compares these different structures and looks at the functional significance of these variations from two main standpoints: energy transfer and quinone exchange.

Item Type:Articles
Status:Early Online Publication
Refereed:Yes
Glasgow Author(s) Enlighten ID:Cogdell, Professor Richard and Nguyen Phan, Cam Tu and Gardiner, Dr Alastair
Authors: Gardiner, A., Nguyen-Phan, T. C., and Cogdell, R. J.
College/School:College of Medical Veterinary and Life Sciences > Institute of Molecular Cell and Systems Biology
Journal Name:Photosynthesis Research
Publisher:Springer
ISSN:0166-8595
ISSN (Online):1573-5079
Published Online:19 May 2020
Copyright Holders:Copyright © The Author(s) 2020
First Published:First published in Photosynthesis Research 2020
Publisher Policy:Reproduced under a Creative Commons license

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
172826DNA-directed construction of three-dimensional photosynthetic assembliesAlasdair ClarkBiotechnology and Biological Sciences Research Council (BBSRC)BB/N016734/1ENG - Biomedical Engineering