The prevalence of cancer associated systemic inflammation: Implications of prognostic studies using the Glasgow Prognostic Score

Dolan, R. and McMillan, D. C. (2020) The prevalence of cancer associated systemic inflammation: Implications of prognostic studies using the Glasgow Prognostic Score. Critical Reviews in Oncology/Hematology, 150, 102962. (doi: 10.1016/j.critrevonc.2020.102962) (PMID:32344318)

[img] Text
214902.pdf - Accepted Version
Restricted to Repository staff only until 18 April 2021.

1MB

Abstract

The prognostic importance of SIR in patients with cancer is widely recognised. More recently it has become clear that the systemic inflammatory response is an important etiologic factor in the development of cancer cachexia. Two recent meta-analysis carried out in 2017 and 2018 were interrogated and the number of patients with specific cancer types were identified. The percentage of patients with operable cancer (n>28,000) who were systemically inflamed varied from 21% to 38%. The percentage of patients with inoperable cancer (n>12,000) who were systemically inflamed varied from 29% to 79%. Overall, the percentage of patients (n>40,000) who were systemically inflamed varied from 28% to 63% according to tumour type. The most commonly studied cancer was colorectal cancer (n∼10,000 patients) and 40% were systemically inflamed.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Dolan, Dr Ross and McMillan, Professor Donald
Authors: Dolan, R., and McMillan, D. C.
College/School:College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
Journal Name:Critical Reviews in Oncology/Hematology
Publisher:Elsevier
ISSN:1040-8428
ISSN (Online):1879-0461
Published Online:18 April 2020
Copyright Holders:Copyright © 2020 Elsevier B.V.
First Published:First published in Critical Reviews in Oncology/Hematology 150:102962
Publisher Policy:Reproduced in accordance with the publisher copyright policy

University Staff: Request a correction | Enlighten Editors: Update this record