An overview of different methods of myocardial protection currently employed peri-transplantation

Avtaar Singh, S. S., Das De, S., Spadaccio, C., Berry, C. and Al-Attar, N. (2017) An overview of different methods of myocardial protection currently employed peri-transplantation. Vessel Plus, 1, pp. 213-229. (doi: 10.20517/2574-1209.2017.26)

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Abstract

Myocardial protection is integral to the functioning of hearts in day to day cardiac surgery. However, due to the longer ischaemic times, it becomes pivotal in the management of organs during transplantation. There are many different strategies employed to ensure diligent and judicious myocardial protection during donor management, transportation of the heart and the post-operative period. Given the limited supply of organs and the increasing waiting lists for heart transplants worldwide, it has become an area of renewed interest with many innovations and inventions using the principles of basic sciences to improve outcomes of transplanted hearts. The heart procurement process encompasses several of the different myocardial protection strategies in tandem to provide the greatest benefit to the recipients. This review looks at the different modalities employed, which include different types of cardioplegia, the role of biomarkers, the cutting-edge novel therapies, hormonal therapies and ischaemic conditioning strategies.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Avtaar Singh, Sanjeet Singh and Al-Attar, Mr Nawwar and Spadaccio, Dr Cristiano and Berry, Professor Colin
Authors: Avtaar Singh, S. S., Das De, S., Spadaccio, C., Berry, C., and Al-Attar, N.
College/School:College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health
College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
Journal Name:Vessel Plus
Publisher:OAE Publishing Inc.
ISSN:2574-1209
Copyright Holders:Copyright © 2017 The Authors
First Published:First published in Vessel Plus 1:213-229
Publisher Policy:Reproduced under a Creative Commons License

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