Automatic diagnosis of the 12-lead ECG using a deep neural network

Ribeiro, A. H. et al. (2020) Automatic diagnosis of the 12-lead ECG using a deep neural network. Nature Communications, 11, 1760. (doi: 10.1038/s41467-020-15432-4) (PMID:32273514) (PMCID:PMC7145824)

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The role of automatic electrocardiogram (ECG) analysis in clinical practice is limited by the accuracy of existing models. Deep Neural Networks (DNNs) are models composed of stacked transformations that learn tasks by examples. This technology has recently achieved striking success in a variety of task and there are great expectations on how it might improve clinical practice. Here we present a DNN model trained in a dataset with more than 2 million labeled exams analyzed by the Telehealth Network of Minas Gerais and collected under the scope of the CODE (Clinical Outcomes in Digital Electrocardiology) study. The DNN outperform cardiology resident medical doctors in recognizing 6 types of abnormalities in 12-lead ECG recordings, with F1 scores above 80% and specificity over 99%. These results indicate ECG analysis based on DNNs, previously studied in a single-lead setup, generalizes well to 12-lead exams, taking the technology closer to the standard clinical practice.

Item Type:Articles
Glasgow Author(s) Enlighten ID:Macfarlane, Professor Peter
Authors: Ribeiro, A. H., Ribeiro, M. H., Paixão, G. M.M., Oliveira, D. M., Gomes, P. R., Canazart, J. A., Ferreira, M. P.S., Andersson, C. R., Macfarlane, P. W., Meira Jr., W., Schön, T. B., and Ribeiro, A. L. P.
College/School:College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > Robertson Centre
Journal Name:Nature Communications
Publisher:Nature Research
ISSN (Online):2041-1723
Copyright Holders:Copyright © 2020 The Authors
First Published:First published in Nature Communications 11:1760
Publisher Policy:Reproduced under a Creative Commons License
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