Systematic review of economic evaluations of primary caries prevention in 2- to 5-year-old preschool children

Anopa, Y., Macpherson, L. and McIntosh, E. (2020) Systematic review of economic evaluations of primary caries prevention in 2- to 5-year-old preschool children. Value in Health, 23(8), pp. 1109-1118. (doi: 10.1016/j.jval.2020.04.1823)

209821.pdf - Published Version
Available under License Creative Commons Attribution Non-commercial No Derivatives.



Objectives: To describe and summarize evidence on economic evaluations (EEs) of primary caries prevention in preschool children aged 2 to 5 years and to evaluate the reporting quality of full EE studies using a quality assessment tool. Methods: A systematic literature search was conducted in several databases. Full and partial EEs were included. The reporting quality of full EE studies was assessed using the Consolidated Health Economic Evaluation Reporting Standards (CHEERS) checklist. Results: A total of 808 studies were identified, and 39 were included in the review. Most papers were published between 2000 and 2017 and originated in the United States and the United Kingdom. The most common type of intervention investigated was a complex multicomponent intervention, followed by water fluoridation. Cost analysis and cost-effectiveness analysis were the most frequently used types of EE. One study employed cost-utility analysis. The proportion of full EEs increased over time. The parameters not reported well included study perspective, baseline year, sensitivity analysis, and discount rate. The CHEERS items that were most often unmet were characterizing uncertainty, study perspective, study parameters, and estimating resources and costs. Conclusions: Within the past 2 decades, there has been an increase in the number of EEs of caries prevention interventions in preschool children. There was inconsistency in how EEs were conducted and reported. Lack of preference-based health-related quality-of-life measure utilization in the field was identified. The use of appropriate study methodologies and greater attention to recommended EE design are required to further improve quality.

Item Type:Articles
Additional Information:Yulia Anopa’s post is funded by the Scottish Government Health Directorate, as part of the Childsmile programme evaluation.
Glasgow Author(s) Enlighten ID:McIntosh, Professor Emma and Macpherson, Professor Lorna and Anopa, Ms Yulia
Authors: Anopa, Y., Macpherson, L., and McIntosh, E.
College/School:College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > Health Economics and Health Technology Assessment
College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing > Dental School
Journal Name:Value in Health
ISSN (Online):1524-4733
Published Online:12 July 2020
Copyright Holders:Copyright © 2020 ISPOR-The Professional Society for Health Economics and Outcomes Research
First Published:First published in Value in Health 23(8):1109-1118
Publisher Policy:Reproduced under a Creative Commons License

University Staff: Request a correction | Enlighten Editors: Update this record