The effect of normobaric hyperoxia on cardiac index in healthy awake volunteers

Harten, J.M., Anderson, K.J., Angerson, W.J., Booth, M.G. and Kinsella, J. (2003) The effect of normobaric hyperoxia on cardiac index in healthy awake volunteers. Anaesthesia, 58(9), pp. 885-888. (doi:10.1046/j.1365-2044.2003.03333.x)

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Abstract

Fifteen healthy volunteers were exposed to a stepwise increase in FIO2 between 0.21 and 1.0, and their haemodynamic responses were measured with a non-invasive transthoracic bio-impedance monitor. There was mean reduction in cardiac index from 3.44 to 3.08 l.min(-1).m(-2) (10.7%, p<0.001). The mean reduction in heart rate was from 77.3 to 69.1 beats.min(-1) (10.5%, p<0.001) and the mean systemic vascular index increased from 2062 to 2221 dyne.s(-1).cm(-5).m(-2) (7.7%, p<0.025). There were no significant changes in stroke index or mean arterial pressure. These changes are similar quantitatively and qualitatively to those previously reported by dye dilution techniques.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Angerson, Dr Wilson and Harten, Dr Johann and Kinsella, Professor John and Anderson, Dr Keith
Authors: Harten, J.M., Anderson, K.J., Angerson, W.J., Booth, M.G., and Kinsella, J.
College/School:College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing > Clinical Specialities
Journal Name:Anaesthesia
ISSN:0003-2409

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