Preschoolers with Autism Spectrum Disorder followed for 2 years: those who gained and those who lost the most in terms of adaptive functioning outcome

Hedvall, Å., Westerlund, J., Fernell, E., Norrelgen, F., Kjellmer, L., Olsson, M. B., Carlsson, L. H., Eriksson, M. A., Billstedt, E. and Gillberg, C. (2015) Preschoolers with Autism Spectrum Disorder followed for 2 years: those who gained and those who lost the most in terms of adaptive functioning outcome. Journal of Autism and Developmental Disorders, 45(11), pp. 3624-3633. (doi: 10.1007/s10803-015-2509-3) (PMID:26123008)

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Abstract

Clinical predictors of 2-year outcome in preschoolers with ASD were studied in a population-based group of very young children with ASD (n = 208). Children who gained the most (n = 30) and lost the most (n = 23), i.e., increased or decreased their adaptive functioning outcome according to the Vineland Composite Score between study entry (T1) and follow-up (T2), 2 years later were compared. Individual factors that differed significantly between the two outcome groups were cognitive level, age at referral, not passing expected milestones at 18 months, autistic type behavior problems and regression. However, logistic regression analysis showed that only cognitive level at T1 (dichotomized into IQ < 70 and IQ ≥ 70) made a unique statistically significant contribution to outcome prediction (p = <.001) with an odds ratio of 18.01. The findings have significant clinical implications in terms of information at diagnosis regarding clinical prognosis in ASD.

Item Type:Articles (Other)
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Gillberg, Professor Christopher
Authors: Hedvall, Å., Westerlund, J., Fernell, E., Norrelgen, F., Kjellmer, L., Olsson, M. B., Carlsson, L. H., Eriksson, M. A., Billstedt, E., and Gillberg, C.
College/School:College of Medical Veterinary and Life Sciences > Institute of Health and Wellbeing > Mental Health and Wellbeing
Journal Name:Journal of Autism and Developmental Disorders
Publisher:Springer Nature
ISSN:0162-3257
ISSN (Online):1573-3432
Published Online:28 June 2015

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