Exploring the powerful phytoarsenal of white grape marc against bacteria and parasites causing significant diseases

Rama, J.-L. R., Mallo, N., Biddau, M. , Fernandes, F., de Miguel, T., Sheiner, L. , Choupina, A. and Lores, M. (2020) Exploring the powerful phytoarsenal of white grape marc against bacteria and parasites causing significant diseases. Environmental Science and Pollution Research, (doi: 10.1007/s11356-019-07472-1) (PMID:31939019) (Early Online Publication)

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Abstract

Natural extracts containing high polyphenolic concentration possess antibacterial, anti-parasitic and fungicidal activities. The present research characterises two extracts based on white grape marc, a winemaking by-product, describing their physicochemical features and antimicrobial capacities. The main components of these extracts are phenolic acids, flavan-3-ols and their gallates and flavonols and their glycosides. As a result of this complex composition, the extracts showed pronounced bioactivities with potential uses in agricultural, pharmaceutical and cosmetic industries. Polyphenol compounds were extracted by using hydro-organic solvent mixtures from the by-product of Albariño white wines (Galicia, NW Spain) production. The in vitro antimicrobial activity of these extracts was evaluated on Gram-positive and Gram-negative bacteria and Apicomplexan and Oomycota parasites. Microbial species investigated are causing agents of several human and animal diseases, such as foodborne illnesses (Bacillus cereus, Escherichia coli, Salmonella enterica, and Toxoplasma gondii), skin infections and/or mastitis (Staphylococcus aureus and Streptococcus uberis), malaria (Plasmodium falciparum) and plant infections as “chestnut ink” or “root rot” (Phytophthora cinnamomi). Both extracts showed activity against all the tested species, being nontoxic for the host. So, they could be used for the development of biocides to control a wide range of pathogenic agents and contribute to the enhancement of winemaking industry by-products.

Item Type:Articles
Additional Information:This research was supported by projects GPC2017/04 (Consolidated Research Groups Program) & ED431E 2018/01 Cross-Research in Environmental Technologies (CRETUS) (Xunta de Galicia, Spain).
Keywords:Anti-parasitic, antibacterial, enhancement of winemaking by-products, grape marc, natural extract, polyphenols.
Status:Early Online Publication
Refereed:Yes
Glasgow Author(s) Enlighten ID:Biddau, Dr Marco and Sheiner, Dr Lilach and Mallo, Dr Natalia
Authors: Rama, J.-L. R., Mallo, N., Biddau, M., Fernandes, F., de Miguel, T., Sheiner, L., Choupina, A., and Lores, M.
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:Environmental Science and Pollution Research
Publisher:Springer
ISSN:0944-1344
ISSN (Online):1614-7499
Published Online:14 January 2020
Copyright Holders:Copyright © 2020 Springer-Verlag GmbH Germany, part of Springer Nature
First Published:First published in Environmental Science and Pollution Research 2020
Publisher Policy:Reproduced in accordance with the publisher copyright policy

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