Wong, M. C.S. et al. (2014) Exposure to air pollutants and mortality in hypertensive patients according to demography: a 10 year case-crossover study. Environmental Pollution, 192, pp. 179-185. (doi: 10.1016/j.envpol.2014.05.025) (PMID:24953346)
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Abstract
This study evaluated whether short term exposures to NO2, O3, particulate matter <10 mm in diameter (PM10) were associated with higher risk of mortality. A total of 223,287 hypertensive patients attended public health-care services and newly prescribed at least 1 antihypertensive agent were followed-up for up to 5 years. A time-stratified, bi-directional case-crossover design was adopted. For all-cause mortality, significant positive associations were observed for NO2 and PM10 at lag 0–3 days per 10 μg/m3 increase in concentration (excess risks 1.187%–2.501%). Significant positive associations were found for O3 at lag 1 and 2 days and the excess risks were 1.654% and 1.207%, respectively. We found similarly positive associations between these pollutants and respiratory disease mortality. These results were significant among those aged ≥65 years and in cold seasons only. Older hypertensive patients are susceptible to all-cause and respiratory disease-specific deaths from these air pollutants in cold weather.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Wang, Professor Haoxiang |
| Authors: | Wong, M. C.S., Tam, W. W.S., Wang, H. H.X., Lao, X.Q., Zhang, D. D., Chan, S. W.M., Kwan, M. W.M., Fan, C. K.M., Cheung, C. S.K., Tong, E. L.H., Cheung, N.T., Tse, L.A., and Yu, I. T.S. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > General Practice and Primary Care College of Medical Veterinary and Life Sciences > School of Health & Wellbeing > Public Health |
| Journal Name: | Environmental Pollution |
| Publisher: | Elsevier |
| ISSN: | 0269-7491 |
| ISSN (Online): | 1873-6424 |
| Published Online: | 20 June 2014 |
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