Boys with Asperger Syndrome grow up: psychiatric and neurodevelopmental disorders 20 years after initial diagnosis

Gillberg, I. C., Helles, A., Billstedt, E. and Gillberg, C. (2016) Boys with Asperger Syndrome grow up: psychiatric and neurodevelopmental disorders 20 years after initial diagnosis. Journal of Autism and Developmental Disorders, 46(1), pp. 74-82. (doi: 10.1007/s10803-015-2544-0) (PMID:26210519)

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We examined comorbid psychiatric and neurodevelopmental disorders in fifty adult males (mean age 30 years) with Asperger syndrome (AS) diagnosed in childhood and followed up prospectively for almost two decades (13–26 years). Only three of the 50 men had never met criteria for an additional psychiatric/neurodevelopmental diagnosis and more than half had ongoing comorbidity (most commonly either ADHD or depression or both). Any psychiatric comorbidity increased the risk of poorer outcome. The minority of the AS group who no longer met criteria for a full diagnosis of an autism spectrum disorder were usually free of current psychiatric comorbidity. The high rate of psychiatric/neurodevelopmental comorbidities underscores the need for a full psychiatric/neurodevelopmental assessment at follow-up of males with AS.

Item Type:Articles
Additional Information:The study was supported by funding from: Centre for Research and Development in Gavleborg and the Child and Adolescent Psychiatric Clinic in Gavle, VG Region Scientific Fund, the Jerring Fund, Wilhelm and Martina Lundgren Foundation, Petter Silfverskiold Foundation, Golje Foundation, AnnMarie and Per Ahlqvist Foundation, the Swedish Child Neuropsychiatry Science Foundation, and the Gillberg Neuropsychiatry Centre.
Glasgow Author(s) Enlighten ID:Gillberg, Professor Christopher
Authors: Gillberg, I. C., Helles, A., Billstedt, E., and Gillberg, C.
College/School:College of Medical Veterinary and Life Sciences > Institute of Health and Wellbeing > Mental Health and Wellbeing
Journal Name:Journal of Autism and Developmental Disorders
ISSN (Online):1573-3432
Published Online:26 July 2015

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