The Autism–Tics, ADHD and other Comorbidities inventory (A-TAC): previous and predictive validity

Mårland, C., Lichtenstein, P., Degl’Innocenti, A., Larson, T., Råstam, M., Anckarsäter, H., Gillberg, C. , Nilsson, T. and Lundström, S. (2017) The Autism–Tics, ADHD and other Comorbidities inventory (A-TAC): previous and predictive validity. BMC Psychiatry, 17, 403. (doi: 10.1186/s12888-017-1563-0) (PMID:29246205) (PMCID:PMC5732476)

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Abstract

Background: Reliable and easy to administer screening instruments focusing on neurodevelopmental disorders and associated conditions are scarce. The Autism–Tics, AD/HD and other Comorbidities inventory (A-TAC) has previously been validated and reporting good– excellent validity for several disorders. This article aims to expand these findings by including more conditions in a substantially larger sample augmented with the Swedish National Patient Register (NPR). Methods: Since 2004 parents of all 9-year-old Swedish twins have been invited to participate in a telephone interview in the Child and Adolescent Twin Study in Sweden, CATSS. The CATSS is linked to the NPR which includes data from in- and outpatient care. Data on neurodevelopmental disorders (A-TAC) collected in CATSS were compared with diagnoses from the NPR. We investigated diagnoses that had been made both before (previous validity) and after (predictive validity) the interview. Results: Sensitivity and specificity of A-TAC scores for predicting earlier or later clinical diagnoses were mostly good–excellent, with values of the area under the curve for a clinical diagnosis of autism spectrum disorder (ASD) of .98, attention deficit hyperactivity disorder (ADHD) .93, learning disorder (LD) .92, and oppositional defiant disorder (ODD) .99, with small differences in terms of previous and predictive analyses. A-TAC provided little validity for eating disorders. Conclusion: The result support previous claims: A-TAC is a broad screening instrument with a particular strength in assessing ASD, ADHD, LD, and ODD at ages 9 and 12, and also provides phenotypic information about other child psychiatric disorders.

Item Type:Articles
Additional Information:Funding: The Child and Adolescent Twin Study in Sweden study was supported by the Swedish Council for Working Life, funds under the ALF agreement, the Söderström-Königska Foundation and the Swedish Research Council (Medicine and SIMSAM). Funding was also received from AnnMari and Per Ahlqvist Foundation and Birgit and Sten A Olsson.
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Gillberg, Professor Christopher
Authors: Mårland, C., Lichtenstein, P., Degl’Innocenti, A., Larson, T., Råstam, M., Anckarsäter, H., Gillberg, C., Nilsson, T., and Lundström, S.
College/School:College of Medical Veterinary and Life Sciences > Institute of Health and Wellbeing > Mental Health and Wellbeing
Journal Name:BMC Psychiatry
Publisher:BMC
ISSN:1471-244X
ISSN (Online):1471-244X
Copyright Holders:Copyright © 2017 The Authors
First Published:First published in BMC Psychiatry 17:403
Publisher Policy:Reproduced under a Creative Commons License

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